Medications That Cause Dry Mouth

Medications That Cause Dry Mouth

There are over 400 medications that can create the dry feeling in your mouth described as “dry mouth.” Most of these medications have an antiadrenergic/anticholinergic impact, suggesting they block particular functions of your body’s systems that help promote watery secretions from glands, like saliva. Research studies state dry mouth can produce problems with swallowing, chewing and dental decay. Familiarize yourself with a couple of frequently used types of medications that can result in oral dryness.

In real most of medications can cause dry mouth in human. Because of most of medications require liquid to work properly, dryness in mouth is come to normal condition after the meds usage. Find below most popular medications that can cause dry mouth:

Antihypertensive Drugs

Studies recommend medications used to treat hypertension like alpha blockers and beta blockers have side effects including dry mouth. Scientists also discovered calcium channel blockers can prevent saliva secretion. Specialists state ACE (angiotensin-converting enzyme) inhibitors used for dealing with high blood pressure as well as diabetes and kidney issues can likewise cause oral dryness.

Urinary Incontinence Drugs

Some drugs recommended to treat urinary incontinence caused by nerve over activity can cause dry mouth. Research studies show antimuscarinic drugs help counter the muscular convulsions that contribute to urinary frequency. However, this antimuscarinic residential or commercial property likewise impacts your body’s ability to secrete saliva — leaving you with that dry mouth sensation.

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Antipsychotic Drugs

Antipsychotic drugs are typically recommended to treat schizophrenia and symptoms connected with bipolar affective disorder, delusional disorder and psychotic depression. Some are also used in the treatment of Huntington’s disease and obsessive-compulsive disorder. A typical side effect of these types of medications is dry mouth. Dry mouth is likewise associated with irregular antipsychotics, which can likewise used be used for schizophrenia, bipolar illness, autism and in significant depressive disorder.


There are several classes of antidepressants, yet most share a typical side effect: dry mouth. Research studies recommend the tricyclic antidepressants (TCAs) and monoamine oxidase inhibitors (MOAIs), which are in some cases used in dealing with Parkinson’s disease, apparently cause dry mouth. Reports state serotonin-norepinephrine reuptake Inhibitors (SNRIs), norepinephrine and dopamine reuptake inhibitors (NDRIs) can develop oral dryness. Experts state particular SSRIs (selective serotonin reuptake inhibitors) with lower anticholinergic activity might have a lower event of dry mouth.


Antibiotics can get rid of bacterial infections in your body. Nevertheless, they can trigger dry mouth, as some have anticholinergic homes. Particular antibiotics are understood to cause dryness in the mouth. Antibiotics used to treat pneumonia, bronchitis, sinus, ear and skin infections can also contribute to oral dryness. This class of drugs is used to treat bacterial infections in various parts of the body and can cause dry mouth. Dry mouth and antibiotics can leave you at risk for establishing a type of fungal infection in your mouth called thrush.

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Antihistamines assist ease runny noses and red, watery eyes, however some apparently have antimuscarinic impacts. These drugs hinder the action of a neurotransmitter in the parasympathetic nerve system. This blocking mechanism can lead to reduce secretion of saliva, leaving you with a dry mouth sensation. There are various types and types of antihistamines like nasal sprays and pills. They are also offered in prescription and over-the-counter kind.

Antidiarrheal/Gastric Medications

Numerous antidiarrheal medications depend on their anticholinergic homes to decrease digestive tract smooth contraction and relax convulsions related to diarrhea. However, these properties can also cause dry mouth. Some antiulcer medications for gastroesophageal reflux disease (GERD) act by hindering the body’s path that produces stomach acids. These have been linked to dry mouth. Proton pump inhibitors, also used to resolve GERD, are understood to add to dry mouth.


Pulmonary diseases are typically treated with bronchodilators. Bronchodilators might cause dry mouth. This takes place due to the fact that most bronchodilators include either beta 2 agonists or anticholinergics, and experts state both of these medications momentarily avoid the production of mucus and saliva. Some bronchodilators used to treat bronchospasms related to chronic obstructive pulmonary disease (COPD), consisting of chronic bronchitis and emphysema, have an antimuscarinic impact, which studies state can prevent salivary secretions in the mouth.

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Pain Medications

Numerous patients usually say they feel “cotton mouth” when taking pain medications. One side effect of typically recommended pain medications is dry mouth. Certain narcotic analgesics used to eliminate pain and cause numbness can likewise produce a dry mouth experience. Opiates in particular are well known for their antisecretory effects. In addition to impacting motility, opiates stimulate absorption of fluid and electrolytes in your body, leaving less fluid available in the mouth.


Diuretics or “water tablets” are commonly linked to xerostomia (severe dry mouth). Diuretics help in reducing the amount of water and salt in your body by passing it through your urine. Lowering fluid assists lower high blood pressure and makes it much easier on your heart to pump. Reports suggest this decrease in fluid corresponds with a decrease in the activity of the salivary glands, leaving less saliva in the mouth.

If you have dry mouth and you know that the cause is certain medications you are taking, then do not rush to stop taking them. It is important to discuss the problem with the doctor who prescribed the medication.

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